Article History
Received: 9 February 2021
Accepted: 6 June 2021
First Online: 27 July 2021
Declarations
:
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. All experimental procedures described here for rodent and human tissues were approved by the appropriate committees at the National Center for Toxicological Research/FDA, including the NCTR Office of Research, the Regulatory Compliance and Risk Management Director and the FDA Research Involving Human Subjects Committee (RIHSC). As determined by the FDA RIHSC, this study did not reach the definition of “Human Subject Research” at 45 CFR 46.102(f) and thus, 45 CFR Part 46 does not apply.
: None of the authors in this manuscript has any conflict of interest.
: This manuscript reflects the views of the authors and does not necessarily reflect those of the Food and Drug Administration.