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Incorporation of a rigid 1,3-diketone-containing fragment led to significantly improved AXL inhibitory activity: design, synthesis, and SAR of the anilinopyrimidine AXL inhibitors

Crossref DOI link: https://doi.org/10.1007/s11030-024-11071-9

Published Online: 2024-12-28

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Hu, Wenyi

Peng, Xia

Ji, Yinchun

Duan, Wenhu

Ai, Jing

Zhan, Zhengsheng
Funding

Funding for this research was provided by:

Shanghai Institute of Materia Medica, Chinese Academy of Sciences (SIMM0320231002, SIMM0120231001)

National Natural Science Foundation of China (81821005, 21702220)
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Text and Data Mining valid from 2024-12-28

Version of Record valid from 2024-12-28
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Article History

Received: 25 October 2024

Accepted: 25 November 2024

First Online: 28 December 2024

Declarations

:

: The authors declare that they have no conflict of interest.

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