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Article History

Received: 5 March 2021

Accepted: 8 July 2021

First Online: 17 July 2021

Declarations

:

: The authors declare that they have no conflict of interest.

: The study was approved by the Deputy of Research and Technology and Ethics Committee of Birjand University of Medical Sciences (Ethic Code: Ir.bums.1394.295). Ethical considerations were considered at all stages of the research. Ethical considerations related to laboratory animals included choosing right animal species for this study, using a minimum number of animals for the study as much as possible, providing appropriate living conditions for the animals, training researchers to understand the animal’s life and physiological conditions (nutrition, health, disease, discomfort and pain, and other physiological and pathological changes in the animal), not using sick animals in the experiment, and finally adhering to ethical protocols in blood sampling and providing conditions for euthanasia of the animals at the end of the study.