Khider, Feriel
Cherbal, Farid http://orcid.org/0000-0001-7338-1252
Boumehdi, Asma-Lamia
Layaida, Karim
Mahfouf, Hassen
Zebboudj, Ferhat
Maaoui, Mustapha
Funding for this research was provided by:
FNRSDT (D01N01UN160420130007)
PRFU (D01N01UN160420180005)
Article History
Received: 17 November 2021
Accepted: 3 February 2022
First Online: 10 February 2022
Declarations
:
: The authors declare non conflict of interest.
: All patients, relatives and parents/legally authorized representatives of the minor subjects tested for <i>APC</i> germline mutations and screened by PCR-direct sequencing and NGS analysis, respectively, signed written informed consent. The study was approved by the institutional review boards and ethical approval was obtained from appropriate institutions (USTHB, EPH Mohamed El Kolli, EPH Bachir Mentouri, University Hospital Mustapha Bacha, FNRSDT D01N01UN160420130007 and PRFU D01N01UN160420180005, 61 participants, start date: 3/1/2012, end date: 5/8/2019).
: Informed consent was obtained from all individual participants and from parents/legally authorized representatives of the minor subjects included in the study.