Ahmad, Imtiaz
de Mello, Julia Eisenhardt
da Silveira, Larissa Menezes
de Aguiar, Mayara Sandrielly Soares
Vizzotto, Marcia
Domingues, William Borges
de Souza, Lucas Petitemberte
Campos, Vinicius Farias
Tavares, Rejane Giacomelli
Spanevello, Roselia Maria
Stefanello, Francieli Moro
Funding for this research was provided by:
Universidade Federal De Pelotas
Article History
Received: 1 December 2025
Accepted: 19 March 2026
First Online: 3 April 2026
Declarations
:
: The authors declared that they have no conflict of interest.
: All animal procedures were consented by the Institutional Ethics Commission (CEEA 5747/2015) and conducted according to the “Guide for the Care and Use of Laboratory Animals” (US National Institutes of Health publication no. 85–23, 1996). The experimental design complied with institutional and international ethical guidelines, including principles of Replacement, Reduction and Refinement (3Rs), and followed the ARRIVE recommendations. All efforts were made to minimize the number of animals used and reduce discomfort or suffering.
: Not applicable.
: Not applicable.