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Engineering overexpressing SYNGR1 inhibited the progression of GBM cells by suppressing the intracellular FGF1-mediated LDs accumulation and cytoskeleton remodeling

Crossref DOI link: https://doi.org/10.1007/s11060-025-05095-w

Published Online: 2025-06-06

Published Print: 2025-09

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wang, Juncheng

Yang, Qiang

Li, Xinlong

Li, Qiao

Zhu, Yufeng

Niu, Liang

Yang, Pengyu

Tian, Guopeng

Ma, Dongming

Yuan, Guoqiang

Pan, Yawen
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82060455, 82360566)

Natural Science Foundation of Gansu Province (22JR5RA966, 22JR5R959)

Natural Science Foundation of Ningxia Hui Autonomous Region (2021AAC03313, 2024AAC03472)

Yinchuan Science and Technology Plan Project (2023SF08)

Lanzhou Science and Technology Bureau Project (2021-RC-97/2023-1-48)

Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital (CY2022-QN-A12, CY2022-QN-B05, CY2021-MS-A09, CY2021-MS-A19)
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Version of Record valid from 2025-06-06
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Article History

Received: 20 April 2025

Accepted: 19 May 2025

First Online: 6 June 2025

Declarations

:

: The present study was approved by The Medical Ethics Committee of The Second Hospital of Lanzhou University (2023 A-163) and People’s Hospital of Ningxia Hui Autonomous Region (2023-NZR-042). All informed consent was obtained from the subject(s) and/or guardian(s). Animal Studies No: D2023-034.

: The authors declare no competing interests.

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