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The Ubiquitination and Degradation of SH2B3 Mediated by MEF2A/WWP2 Axis Restores Microglial Homeostasis to Alleviate Cerebral Microvascular Endothelial Cell Injury in Ischemic Stroke

Crossref DOI link: https://doi.org/10.1007/s11064-025-04406-x

Published Online: 2025-05-23

Published Print: 2025-06

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lin, Si-xian

Shi, Chenglong

Zhao, Lei

Xian, Lei

Yang, Wenwu

Wang, Zhenyu

Qin, Longjie

Min, Xiao-li

Yu, Jiasheng
Funding

Funding for this research was provided by:

the National Natural Science Foundation of China (No. 82260246)

Yunnan Province applied basic research joint project (No. 202301AY070001-271)

Academic leader of the talent team project of the Second Affiliated Hospital of Kunming Medical University (No. RCTDXS-202307)
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Text and Data Mining valid from 2025-05-23

Version of Record valid from 2025-05-23
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Article History

Received: 30 December 2024

Revised: 18 April 2025

Accepted: 22 April 2025

First Online: 23 May 2025

Declarations

:

: All animal experiments were approved by Ethics Committee of Kunming Medical University.

: The authors declare no competing interests.

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