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The Impact of Drug Properties and Severity of Obesity on Renal Drug Clearance Through Glomerular Filtration and Active Tubular Secretion: A Systematic Analysis Using PBPK Modeling

Crossref DOI link: https://doi.org/10.1007/s11095-025-03885-5

Published Online: 2025-06-27

Published Print: 2025-07

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhang, Tan

Calvier, Elisa A. M.

Krekels, Elke H. J.

Knibbe, Catherijne A. J. https://orcid.org/0000-0001-9893-4415
Funding

Funding for this research was provided by:

China Scholarship Council (201906010328)
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Text and Data Mining valid from 2025-06-27

Version of Record valid from 2025-06-27
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Article History

Received: 6 January 2025

Accepted: 13 June 2025

First Online: 27 June 2025

Declarations

:

: None of the authors have a conflict of interest to declare.

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