Funding for this research was provided by:
Text and Data Mining valid from 2019-04-10
First Online: 10 April 2019
Compliance with ethical standards
: Lopes: Research grant: Bristol-Myers Squibb, GlaxoSmithKline, Medtronic, Pfizer; Consultant/Advisory Board: Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Daiichi Sankyo, Medtronic, Merck, Portola, GlaxoSmithKline, Pfizer. Alexander: Research grant: AstraZeneca, Bristol-Myers Squibb, Boehringer Ingelheim, CSL Behring, Sanofi, Tenax Therapeutics; Consultant/Advisory Board: Cempra, CryoLife, CSL Behring, Pfizer, Portola Pharmaceuticals, VasoPrep Surgical. Hijazi: Honoraria: Boehringer Ingelheim, Roche Diagnostics, Pfizer and Bristol-Myers Squibb; Consultant/Advisory board: Pfizer, Bristol-Myers Squibb, Roche Diagnostics, and Merck, Sharp & Dohme. Hylek: Consultant: Bayer, Boehringer Ingelheim, Bristol Myers Squibb/Pfizer, Daiichi-Sankyo, Johnson & Johnson; Research grant: Bristol Myers Squibb/Pfizer, Johnson & Johnson. Gersh: Consulting fees/Honoraria: Xenon Pharmaceuticals; Data monitoring board: Armetheon Inc, Baxter Helathcare Corporation, CardioVascular Research Foundation, Janssen Research & Development, MEDTRONIC, Mount Sinai St. Lukes, Teva Pharmaceuticals, Thrombosis Research Institute; Other: Boston Scientific, Cipla Limited, Janssen Scientific Affairs LLC, St. Jude Medical, Inc. Garcia: Consultant/Advisory Board: BMS/Pfizer, Genzyme, Boehringer Ingelheim, Incyte, Alexion. Research Support: Daiichi Sankyo, Janssen, Incyte. Verheugt: Honoraia/Consultant: Bayer Healthcare, Boehringer-Ingelheim, BMS/Pfizer, and Daiichi-Sankyo. Hanna: An employee of the sponsor (BMS), received salary and stock as part of his employment compensation. Vinereanu: Research grant: GlaxoSmithKline, Pfizer, Bristol-Myers Squibb. Granger: Research Grant: Armetheon, AstraZeneca, Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Daiichi, GlaxoSmithKline, Janssen, Medtronic Foundation, Novartis, Pfizer, The Medicines Company; Consultant/Advisory Board: AstraZeneca, Bayer, Boehringer Ingelheim, Boston Scientific, Bristol-Myers Squibb, Daiichi Sankyo, Eli Lilly, Gilead Sciences, Inc, GlaxoSmithKline, Hoffman LaRoche, Janssen, Medtronic, Novartis, Pfizer, The Medicines Company, Verseon. Guimarães, Thomas, Hellkamp, and Flaker authors declare that they have no conflict of interest.
: All procedures performed in studies involving human participants were in accordance with ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
: Informed consent was obtained from all participants included in the study.