Hermosa, Juan Luis Rodríguez
Rubio, Myriam Calle
Cidranes, Ernesto Delgado
Walther, José Luis Álvarez-Sala
Blasco, Víctor Javier Montero
Uriel, María Ángela Velacoracho
Rondán, Baldomero Fernández
Funding for this research was provided by:
Torytrans S.L.
Article History
Received: 22 September 2025
Revised: 20 February 2026
Accepted: 15 April 2026
First Online: 29 April 2026
Declarations
:
: The project was approved by the Ethics Committee of the Clinical Hospital of San Carlos (C.I. 20/485-EC_P) on July 24, 2021 and authorized by the Spanish Agency of Medicines and Medical Devices (AEMPS; 835/20/EC) on August 28, 2021.
: All participants signed an informed consent prior to the enrollment in the study, in accordance with the principles of the Declaration of Helsinki and Spain’s new Organic Law 3/2018 on the Protection of Personal Data and the Guarantee of Digital Rights, effective since December 7, 2018.
: JLRH has received speaker fees or consulting fees or support for attending meetings from AstraZeneca, Bial, CSL Behring, GlaxoSmithKline, Grifols, Menarini and Zambon. MCR has received speaker fees or consulting fees or support for attending meetings from AstraZeneca, Bial, Chiesi, CSL Behring, Gebro, GlaxoSmithKline, Menarini, Grifols, Sanofi and Zambon. EDC, JLAW, VJM, MAV and BF declare that they have no competing interests. VJMB and MAVU are employees of Torytrans S.L.