Chen, Kai-Yun https://orcid.org/0000-0002-2941-3197
Hsueh, Shih-Chang https://orcid.org/0009-0002-0838-0223
Parekh, Pathik https://orcid.org/0000-0002-4385-751X
Batsaikhan, Buyandelger https://orcid.org/0000-0002-1505-9334
Tweedie, David https://orcid.org/0000-0002-8446-4544
Luo, Weiming
Patel, Chirag
Chiang, Yung-Hsiao https://orcid.org/0000-0002-8426-4016
Bambakidis, Nicholas https://orcid.org/0000-0002-6780-9432
Hoffer, Barry J.
Huang, Chi-Zong
Yu, Seong-Jin
Wu, Kuo-Jen
Wang, Yun
Hong, Eunji
Kim, Dong Seok
Greig, Nigel H. https://orcid.org/0000-0002-3032-1468
Funding for this research was provided by:
National Institute on Aging (AG000994)
Korea Dementia Research Center (RS-2024-0034124913)
Korea Drug Development Fund (KDDF RS-2024-00338017)
Institute for Information Industry, Ministry of Science and Technology, Taiwan (MOST 111-2314-B-038 -134 -MY3)
Taipei Medical University-Case Western University Cooperative Research Agreement (TMU 112-3805-001-400)
School of Medicine, Case Western Reserve University
National Institute on Aging
Article History
Received: 16 January 2025
Accepted: 17 February 2025
First Online: 17 March 2025
Declarations
:
: This is a preclinical (non-clinical) research study that does not require ethics approval and consent to participate of human subjects. All preclinical animal studies were undertaken on fully approved Institutional Animal Care and Use Committee protocols (see Materials and Methods, Section C).
: All authors have read, approved, and have provided their consent for submission and publication of the present manuscript in GeroScience.
: DSK and EH are employed by and have stock in Aevis Bio Inc., which has patent coverage on 3-MP. All other authors declare a lack of conflicts of interest.