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Increased quadriceps intermuscular adipose tissue in chronic liver disease is associated with an altered muscle transcriptome compared with healthy age matched controls

Crossref DOI link: https://doi.org/10.1007/s11357-025-01982-2

Published Online: 2025-11-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Quinlan, J. I. https://orcid.org/0000-0002-1205-7069
Nicholson, T.

Bell, C.

Dhaliwal, A.

Williams, F. R.

Allen, S. L.

Choudhary, S.

Rowlands, A. V.

Elsharkawy, A. M.

Armstrong, M. J.

Greig, C. A.

Lord, J. M.

Jones, S. W.

Breen, L.
Funding

Funding for this research was provided by:

Birmingham Biomedical Research Centre (BRC-1215- 20009)
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Text and Data Mining valid from 2025-11-14

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Article History

Received: 3 October 2025

Accepted: 24 October 2025

First Online: 14 November 2025

Declarations

:

: The study was approved by the Health Research Authority - West Midlands Solihull Research Ethics Service Committee Authority (REC reference: 18/WM/0167) and the study has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. All patients provided written informed consent. (ClinicalTrials.govIdentifier: NCT04734496). Graphical abstract created in BioRender. Macleod, M. (2025) .

: The authors declare no competing interests.

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