Li, Mengze
Song, Zeyuan
Reed, Eric
Karagiannis, Tanya T.
Andersen, Stacy
Brent, Michael
Mateusiak, Chase
Acharya, Sandeep
Jung, Wooseok J.
Liao, Shu
Wojczynski, Mary K.
Feitosa, Mary F.
O’Connell, Jeffrey R.
Montasser, May E.
Thorpe, Roland J. Jr.
Arbeev, Konstantin
Milman, Sofiya
Tai, Albert
Perls, Thomas T.
Sebastiani, Paola
Monti, Stefano https://orcid.org/0000-0002-9376-0660
Funding for this research was provided by:
National Institute on Aging (U19 AG063893)
National Institute on Aging (UH2/UH3 AG064704)
Article History
Received: 9 October 2025
Accepted: 26 December 2025
First Online: 21 February 2026
Declarations
:
: This study was conducted in accordance with the relevant local and international ethical guidelines. All enrolled participants (or their legal guardian or representative, when applicable) provided informed consent. All study personnel and data analysts have completed and maintained current human-subjects research training under IRB oversight. All participant data used, including phenotypical data, genetic data, and RNA-seq data, were de-identified and are stored on secure servers with restricted access.
: The authors declare no competing interests.