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Authors
Gauci, Sarah https://orcid.org/0000-0002-1907-1066
Mengist, Belayneh
Lotfaliany, Mojtaba
Forbes, Malcolm
Asoudeh, Farzaneh
Zhang, Deb Junyi
Orchard, Suzanne G.
Owen, Alice J.
Clayton-Chubb, Daniel
Woods, Robyn L.
McNeil, John J.
Ryan, Joanne
Berk, Michael
O’Neil, Adrienne
Mohebbi, Mohammadreza
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Funding
Funding for this research was provided by:
National Institute on Aging (U01AG029824)
National Cancer Institute at the National Institutes of Health (U19AG062682)
National Health and Medical Research Council (334047)
National Health and Medical Research Council (1127060)
National Health and Medical Research Council (GNT1182301)
National Health and Medical Research Council (1173690)
National Health and Medical Research Council (GNT2017131)
National Health and Medical Research Council (2009295)
Monash University
Victorian Cancer Agency
Deakin University (DUPR-0000018830)
Deakin University
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Article History
Received: 17 December 2025
Accepted: 17 April 2026
First Online: 6 May 2026
Declarations
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: The ASPREE trial was conducted in accordance with the 2008 Declaration of Helsinki and approved by the ethics review board at each participating institution. Monash University Human Research Ethics Committee and the Alfred Hospital Human Research Ethics Committee approved the ALSOP and ASPREE-XT (Monash 4HRECCF11/1935/2011001094 and Alfred HREC 593/17). All participants provided their written informed consent to participation. The current secondary analysis was approved by the Monash University Human Research Ethics Committee.
: S.G. and A.O. are affiliated with the Food & Mood Centre, Deakin University, which has received research funding support from Be Fit Food, Bega Dairy and Drinks, and the a2 Milk Company and philanthropic research funding support from the Waterloo.Foundation, Wilson Foundation, the JTM Foundation, the Serp Hills Foundation, the Roberts Family Foundation, and the Fernwood Foundation. The authors report no other conflicts of interest.During the preparation of this work, the authors used OpenAI ChatGPT in order to help with editing and improve the readability of the manuscript. After using this tool, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication.
