Krogstad, Liv S. https://orcid.org/0000-0002-5312-6526
Teppen, Markus Augustin https://orcid.org/0009-0007-6239-8092
Mjønes, Harald S. https://orcid.org/0009-0003-6638-0675
Brewer, Jonathan R. https://orcid.org/0000-0002-3444-1715
Park, Thomas https://orcid.org/0000-0002-2447-2948
Geiseler, Samuel https://orcid.org/0000-0002-1332-3816
Morland, Cecilie https://orcid.org/0000-0002-1776-1821
Funding for this research was provided by:
Universitetet i Oslo
National Science Foundation (2201647)
University of Oslo
Article History
Received: 6 January 2026
Accepted: 11 September 2026
First Online: 17 September 2026
Declarations
Ethics approval: Animal work with mice was approved by the Norwegian Animal Use and Care Committee (FOTS #14204, approval date 19 April 2018). Animal work with naked mole rats was approved by the University of Illinois Chicago Institutional Animal Care and Use Committee. The university’s Animal Welfare Assurance Number D16-00290 (A3460-01) is on file with the Office of Laboratory Animal Welfare (OLAW), National Institutes of Health. The work is reported in compliance with the Animal Research: Reporting in Vivo Experiments (ARRIVE) guidelines, version 2.0 [ ]. In total, 8 NMR (four young and four middle-aged) and 9 mouse (five young and four middle-aged) were used in this study. All experiments involving live animals were conducted in strict accordance with the national and regional ethical guidelines, and animals were treated by Federation of Laboratory Animal Science Association (FELASA) certified personnel.
Informed consent: No human subjects were involved in this study.
Competing interests: The authors declare no competing interests.