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Pyrimidine Derivative, (E)-N-[4-(4-Chlorophenyl)-6-(4-Methylphenyl)Pyrimidin-2-yl]-1-(Furan-2-yl)Methanimine, Named BN5 Ameliorates Cognitive Dysfunction and Regulates esr1 and esr2b Expression in Female In Vivo Zebrafish Alzheimer Model

Crossref DOI link: https://doi.org/10.1007/s11481-025-10248-9

Published Online: 2025-10-21

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Aswinanand, B.

Palani, Kumar Nallasivan

Santhanam, Sanjai Dharshan

Ramamurthy, Karthikeyan

Palaniappan, Senthilkumar

Arasu, M. Valan

Guru, Ajay

Muthuramamoorthy, Muthumareeswaran

Kumaradoss, Kathiravan Muthu

Arockiaraj, Jesu
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Text and Data Mining valid from 2025-10-21

Version of Record valid from 2025-10-21
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Article History

Received: 3 January 2025

Accepted: 3 September 2025

First Online: 21 October 2025

Declarations

:

: Animal studies have been carried out as per the approval (No. IAEC/313/2023) of Institutional Animal Ethical Committee following the guidelines of CPCSEA.

: All of the authors consent to the publication of the identifiable details of the text.

: During the writing of this manuscript, the authors used Grammarly to improve its grammar and readability. After using these tools, the authors reviewed and edited the content as needed and took full responsibility for the publication's content.

: The authors declare no competing interests.

: All authors certify that they have no affiliations with or involvement in any organization or entity with any financial or non-financial interest in the subject matter or materials discussed in this manuscript.

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