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Article History

First Online: 26 June 2019

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: This work was funded by Sun Pharmaceutical Industries, Inc., Princeton, NJ, USA. The authors received no compensation for the creation of this review. Medical writing and editorial support were provided by Marie-Louise Ricketts, PhD, of AlphaBioCom, LLC, King of Prussia, PA, USA.

: Ralf Gutzmer serves as a consultant to Almirall, Amgen, Bristol-Myers Squibb, Incyte, LEO Pharma, Merck Serono, Merck Sharp Dohme, Novartis, Pfizer, Pierre-Fabre, Roche, Sanofi Genzyme, Sun Pharmaceutical Industries, Inc., Takeda, and 4SC; has received travel grants and honoraria for lectures from Almirall, Amgen, Astra-Zeneca, Bristol-Myers Squibb, Merck Serono, Merck Sharp Dohme, Novartis, Pierre-Fabre, Roche, and Sun Pharmaceutical Industries, Inc.; and received research funding from Amgen, Johnson & Johnson, Merck-Serono, Novartis, and Pfizer. James A. Solomon serves as consultant to Lilly, Mayne, Sun Pharmaceutical Industries, Inc., and Ameriderm; and has received research funding from Allergan, Altana, Anacor, Apotex, AstraZeneca, Asubio, Barrier, Basilea, Bayer, Boehringer Ingelheim, Biocryst, Braintree, Centocor, Celtic, Chilter, Cipher, Clynsis, Concentrics, Covance, CuTech, Dermira, Dow, Eli Lilly, Encorium, Epithany, Galderma, Genentech, Genomics, GlaxoSmithKline, Glenmark, Health Decisions, HedgePath Pharmaceutical, Hill, ICON, Incyte, Inventiv, Kendle International, LEO Pharmaceuticals, Manhattan, Maruho, MAVIS, Merck, Novartis, Noven, Novum, Omnicare, ParaPro Inc, Parexel, Peplin, Pfizer, PharmaNet, Polynoma, PPD Development, PRA, Premier, Pro Trials, Quintiles, Regeneron, Research Sample Bank, Rho, Roche, Sanofi-Aventis, SciQuus, Serentis, SGS, Steifel, Sterling Bio, Symbio, Taisho, Taro, Teva Pharmaceutical, Theraputics Clinical Research, TKL Research, Tolmar, Topaz, Vanda, and Worldwide Clinical Trials.