Trippett, Tanya
Toledano, Helen
Campbell Hewson, Quentin
Verschuur, Arnauld
Langevin, Anne-Marie
Aerts, Isabelle
Howell, Lisa
Gallego, Soledad
Rossig, Claudia
Smith, Amy
Patel, Darshak
Pereira, Leonardo R.
Cheeti, Sravanthi
Musib, Luna
Hutchinson, Katherine E.
Devlin, Clare
Bernardi, Ronald
Geoerger, Birgit
Clinical trials referenced in this document:
Documents that mention this clinical trial
Cobimetinib in Pediatric and Young Adult Patients with Relapsed or Refractory Solid Tumors (iMATRIX-cobi): A Multicenter, Phase I/II Study
https://doi.org/10.1007/s11523-022-00888-9
Funding for this research was provided by:
F. Hoffmann-La Roche Ltd/Genentech, Inc.
Article History
Accepted: 26 April 2022
First Online: 17 June 2022
Declarations
:
: The study was funded by F. Hoffmann-La Roche Ltd/Genentech, Inc.
: TT reports consultancy fees from F. Hoffmann-La Roche Ltd. HT reports lecture fees from AstraZeneca and Roche. SG reports personal fees from Bayer, EUSA Pharma, and LOXO Oncology. CR reports personal fees from Amgen, BMS, Celgene, Genentech, Inc., Novartis, Pfizer, and F. Hoffmann-La Roche Ltd. DP was an employee of F. Hoffman-La Roche Ltd. at the time of study conduct. LM was an employee of Genentech, Inc. at the time of study conduct. LRP is an employee of F. Hoffmann-La Roche Ltd. SC, KEH, CD, and RB are employees of and stock-holders in F. Hoffmann-La Roche Ltd/Genentech, Inc. All other authors declare no competing interests.
: This study was performed in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
: Written informed consent was obtained from parents, patients, or legal representatives.
: Not applicable.
: Qualified researchers may request access to individual patient level data through the clinical study data request platform (ExternalRef removed). Further details on Roche's criteria for eligible studies are available here (ExternalRef removed). For further details on Roche's Global Policy on the Sharing of Clinical Information and how to request access to related clinical study documents, see here (ExternalRef removed).
: Not applicable.
: TT and BG contributed to the conception and design of the study. All authors contributed to collection and assembly of data, and to data analysis and interpretation. All authors critically reviewed the manuscript, provided final approval, and agreed to be accountable for all aspects of the work.