Yang, Tianwu https://orcid.org/0009-0005-0856-4497
Rasmussen, Anna Sofie Buhl https://orcid.org/0000-0002-4997-2914
Weimann, Allan
Thastrup, Maria https://orcid.org/0000-0001-9950-5911
Rank, Cecilie Utke https://orcid.org/0000-0003-0578-3887
Als-Nielsen, Bodil
Malmros, Johan https://orcid.org/0000-0002-7274-2957
Wik, Hilde Skuterud https://orcid.org/0000-0002-1035-5521
Lohi, Olli https://orcid.org/0000-0001-9195-0797
Overgaard, Ulrik
Johannsdottir, Inga Maria Rinvoll
Vaitkeviciene, Goda https://orcid.org/0000-0001-6724-8164
Dalhoff, Kim https://orcid.org/0000-0002-5548-6381
Schmiegelow, Kjeld https://orcid.org/0000-0002-0829-4993
Lund, Trine Meldgaard https://orcid.org/0000-0001-8598-2880
Funding for this research was provided by:
Børnecancerfonden (2021-7410, 2022-8178)
Arvid Nilssons Fond
Director Michael Hermann Nielsen’s Memorial Foundation (2022-0097724)
Engineer Otto Christensen's Foundation
Manufacturer Einar Willumsen’s Memorial Foundation
Det Sundhedsvidenskabelige Fakultet, Københavns Universitet
Copenhagen University
Article History
Received: 23 April 2025
Accepted: 17 August 2025
First Online: 8 September 2025
Declarations
:
: This research is funded by the University of Copenhagen and the Copenhagen University Hospital. The work was supported by Danish Childhood Cancer Foundation (project number 2021-7410 and 2022-8178), Arvid Nilssons Foundation, Director Michael Hermann Nielsen’s Memorial Foundation (project number 2022-0097724), Engineer Otto Christensen's Foundation, and Manufacturer Einar Willumsen’s Memorial Foundation.
: Tianwu Yang, Anna Sofie Buhl Rasmussen, Allan Weimann, Maria Thastrup, Cecilie Utke Rank, Bodil Als-Nielsen, Johan Malmros, Hilde Skuterud Wik, Olli Lohi, Overgaard, Inga Maria Rinvoll Johannsdottir, Goda Vaitkeviciene, Kim Dalhoff, Kjeld Schmiegelow, and Trine Meldgaard Lund have no conflicts of interest that are directly relevant to the content of this article.
: This study has received approval from the local ethics committee. All procedures involving human subjects were performed following the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
: All participants provided written informed consent.
: Not applicable.
: The data of this study are available from the corresponding author upon reasonable request.
: Not applicable.
: TY: conceptualization; data curation; formal analysis; investigation; methodology; software; validation; visualization; writing (original draft); writing (review and editing). ASBR: conceptualization; data curation; investigation; resources; writing (review and editing). AW and MT: data curation; resources; writing (review and editing). CUR, BA-N, JM, HSW, OL, UO, IMRJ, and KD: resources; writing (review and editing). KS: funding acquisition; project administration; resources; supervision; writing (review and editing). TML: conceptualization; funding acquisition; project administration; resources; supervision; writing (review and editing).