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In Silico Comparison of Rifampicin and 25-desacetyl Rifampicin-Induced PXR-Mediated CYP450 Transcriptional Response in 3D Primary Human Hepatocytes

Published Online: 2026-03-06

Published Print: 2026-04

Authors

Kahiya, Ellen Tanaka

Smutný, Tomáš

Smutná, Lucie

Duintjer Tebbens, Jurjen

Pávek, Petr

Bernhauerová, Veronika https://orcid.org/0000-0002-5595-4579
Funding

Funding for this research was provided by:

Univerzita Karlova v Praze (PRIMUS/22/MED/017)

Univerzita Karlova v Praze (UNCE/24/MED/008)

Ministerstvo Školství, Mládeže a Tělovýchovy (CZ.02.01.01/00/22_008/0004607)

Grantová Agentura České Republiky (22-05167S)
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Text and Data Mining valid from 2026-03-06

Version of Record valid from 2026-03-06
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Article History

Received: 31 July 2025

Accepted: 7 February 2026

First Online: 6 March 2026

Change Date: 3 April 2026

Change Type: Update

Change Details: The missing ESM file has been updated

Document is current