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Authors
Zagorchev, Lyubomir https://orcid.org/0000-0001-6239-9641
Wenzel, Fabian
Gooßen, André
Fläschner, Nick
Li, Chen
Hyde, Damon E.
Cerny, Andreas
Hotte, Philip
Orr, Tim
Culbreth, Brady
Larson, Paul
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Funding
Funding for this research was provided by:
ClearPoint Neuro
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Article History
Received: 12 November 2025
Accepted: 3 April 2026
First Online: 28 April 2026
Declarations
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: The authors are affiliated with ClearPoint Neuro and Philips. Their involvement is solely scientific, with no financial or conflict of interest that could compromise the objectivity or integrity of the presented work. This manuscript aims to detail the methodology behind model-based registration and to outline the quantitative performance analysis conducted to validate its accuracy. It is important to note that the model-based registration described herein is not currently available in any commercially released ClearPoint Neuro or Philips products.
