Zhang, Xiao-lei
Hu, Hai-ming
Yao, Qun-feng
Sun, Xiong-jie
Yao, Xiao-wei
Cao, Lu
Ma, Jun
Liu, Hong-tao https://orcid.org/0000-0003-0149-6389
Funding for this research was provided by:
National Natural Science Foundation of China (81473788)
National Key Research and Development Program (2020YFC0845800)
Hubei Provincial Natural Science Foundation and Traditional Chinese Medicine Innovation and Development-of China (2023AFD156)
Educational Commission of Hubei Province of China (D20212003)
Wuhan Knowledge Innovation Project (NO. 2022020801010420)
Hubei Provincial Natural Science Joint Fund (no.2024AFD298)
Wuhan Knowledge Innovation Project (NO. 2023020201020794)
Article History
Received: 25 May 2025
Revised: 19 November 2025
Accepted: 21 November 2025
First Online: 8 January 2026
Declarations
:
: The authors have no competing interests to declare that are relevant to the content of this article.
: Not applicable.
: All procedures involving animals were approved by the Animal Ethics Committee of Hubei University of Traditional Chinese Medicine (Approval No. HUCMS 00128768) and conducted in accordance with the National Act on the Use of Experimental Animals (China). The study was performed in compliance with the ARRIVE 2.0 guidelines and the NIH Guide for the Care and Use of Laboratory Animals. All efforts were made to minimize animal suffering, including the use of isoflurane anesthesia for blood collection and humane endpoints. No human participants were involved in this study.