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Authors
Liu, Xin
Xu, Qing-qing
Zhang, Yi-bo
Yuan, Shi-yu
Huang, Wen-li
Pi, Ming-shan
Xiong, Qi
Gui, Yu-ran
Deng, Shi-chao
Wan, Ling
Xiao, Yi-fan
Wang, Xiao-chuan
Shu, Xi-ji
Xia, Yi-yuan https://orcid.org/0000-0001-7833-0497
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Funding
Funding for this research was provided by:
Hubei Provincial Natural Science Foundation of China for Distinguished Young Scholars (Grant No. 2022CFA104)
Key Research and Development Program of Wuhan (Grant No. 2024020802030159)
The National Natural Science Foundation of China (Grant No. 82371195)
Research Fund of Jianghan University (Grant No. 2022XKZX26)
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Article History
Received: 24 June 2025
Revised: 31 December 2025
Accepted: 5 January 2026
First Online: 5 February 2026
Declarations
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: The authors declare that they have no conflicts of interest.
: All mice in this research were accommodated and situated in the Medicine Animal Center of Jianghan University, and all procedures were conducted in full accordance with the guidelines set by the Medical Ethics Committee of Jianghan University (Approval No. JHDXLL2025-011). Human Brain samples were sourced from the Chinese Brain Bank Center (China), all specimens were derived from the cerebral cortex and were collected with written consent from the respective family members of the deceased. The study was sanctioned by the Medical Ethical Committee of Jiang Han University (Approval No. JHDXLL2022-043).
: Written consent for publication was collected from the respective family members of the deceased.
