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Article History

Received: 20 December 2025

Accepted: 24 February 2026

First Online: 14 March 2026

Declarations

:

: Antoine Choppin and Aya Tonouchi are employees of LPIXEL Inc., and data analysis using AI software was provided by LPIXEL Inc. The other authors declare no conflicts of interest relevant to this study.

: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013). The study was approved by the institutional review boards of Kanazawa University and Ishikawa Health Service Association. Because all participants had provided broad written and oral consent at the time of the routine checkup for the future research use of de-identified clinical data and imaging (with an opt-out option), the requirement for additional individual informed consent for this retrospective analysis was waived.

: Broad written and oral informed consent for future research use of de-identified clinical data and imaging was obtained as part of the routine checkup process; participants could withdraw consent (opt-out) according to the standard procedure of the screening program.