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Article History

Received: 3 July 2025

Accepted: 6 October 2025

First Online: 23 November 2025

Declarations

:

: This study was carried out in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. The protocol was approved by the Committee on the Ethics of Animal Experiments of the Tianjin Kangting Biological Engineering Group Co. ltd(KIBS, KIBS-IACUC-2022-012-1).. All surgery was performed under sodium pentobarbital anesthesia, and all efforts were made to minimize suffering.

: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

: The authors declare no competing interests.