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Article History

Received: 6 May 2024

Accepted: 8 June 2024

First Online: 8 August 2024

Compliance with ethics guidelines

: <b>Conflicts of interest</b> Shubei Chen, Dianjia Liu, Bingyi Chen, Zijuan Li, Binhe Chang, Chunhui Xu, Ningzhe Li, Changzhou Feng, Xibo Hu, Weiying Wang, Yuanliang Zhang, Yinyin Xie, Qiuhua Huang, Yingcai Wang, Stephen D. Nimer, Zhu Chen, Lan Wang, and Xiaojian Sun declare no potential conflicts of interest. Saijuan Chen is one of Editors-in-Chief of Frontiers of Medicine, who was excluded from the peer-review process and all editorial decisions related to the acceptance and publication of this article. Peer-review was handled independently by the other editors to minimise bias.

: All the procedure of this study was approved by the Institutional Review Board of the Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine. The animal studies were approved by the Committee of Animal Use at Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences. All institutional and national guidelines for the care and use of laboratory animals were followed.