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Reproductive Dysfunction and Testicular Epigenetic Alterations in Male Rats with Experimental Amebiasis: Evaluation of SPATA6 Methylation and Therapeutic Outcomes

Crossref DOI link: https://doi.org/10.1007/s11686-025-01133-9

Published Online: 2025-10-28

Published Print: 2025-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Noor, Alaa A. https://orcid.org/0009-0009-7866-5698
Saleh, Hazar S. https://orcid.org/0000-0002-1029-1775
AL-Abady, Fadhil A.
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Text and Data Mining valid from 2025-10-28

Version of Record valid from 2025-10-28
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Article History

Received: 24 June 2025

Accepted: 26 August 2025

First Online: 28 October 2025

Declarations

:

: The authors declare no competing interests.

: All experimental procedures involving animals were reviewed and approved by the Thi-Qar Ethical Committee for Animal Research (Approval No. 7/54/1727). The study was conducted in strict accordance with both institutional and national guidelines for the care and use of laboratory animals. Every effort was made to minimize animal suffering and reduce the number of animals used. Fecal samples for parasite isolation were obtained from adult patients after obtaining written informed consent. The procedure was reviewed and approved by the Thi-Qar University Human Research Ethics Committee (Approval No. 7/54/225, dated 15/02/2024), in accordance with the ethical principles outlined in the Declaration of Helsinki.

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