Hany, Mohamed https://orcid.org/0000-0001-6650-8112
Hozien, Adel Ibrahim https://orcid.org/0000-0001-8715-2549
Mohamed Hussein, Heba Abdel Samie
El-Sayes, Islam
Hashem, Engi Yousry
Elmongui, Ehab https://orcid.org/0009-0002-9497-8159
El Shamarka, Ahmed https://orcid.org/0000-0002-7257-9969
El Ansari, Walid https://orcid.org/0000-0003-0961-1302
Funding for this research was provided by:
Alexandria University
Article History
Received: 31 October 2025
Revised: 5 January 2026
Accepted: 8 February 2026
First Online: 31 March 2026
Declarations
:
: The study was conducted in accordance with the Declaration of Helsinki and was reviewed and approved by the Ethics Committee of the Medical Research Institute, Alexandria University (IORG0008812, IRB00010526, Serial Number: E/C. S/N. R28/2023), and the ethical committee of the Faculty of Medicine, Alexandria University (IRB00012098; FWA No: 00018699; Serial Number: 0306158) in May 2023. It was also registered in the Clinical Trials Registry (NCT07100314). Written informed consent was obtained from all participants before enrollment.
: Not applicable.
: The authors declare no competing interests.