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Upregulated PCSK9 Level Contributes to Human Pulmonary Microvascular Endothelial Cell Apoptosis in Cigarette Smoke Extract-Induced COPD Models Through TLR4/NF-kappaB Pathway Activation

Crossref DOI link: https://doi.org/10.1007/s12010-025-05328-8

Published Online: 2025-07-17

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Li, Yunxia

He, Fengzhen

Zhao, Shasha

Zhang, Chunli

Chen, Xueyang

Luo, Xiang
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Text and Data Mining valid from 2025-07-17

Version of Record valid from 2025-07-17
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Article History

Received: 26 November 2024

Accepted: 27 June 2025

First Online: 17 July 2025

Declarations

:

: The Animal Research Committee of The First Affiliated Hospital of Xinxiang Medical University approved all animal experiments. The experiments were conducted according to the International Animal Research Guiding Principles. Ethics Committee of The First Affiliated Hospital of Xinxiang Medical University approved the clinical materials for research use.

: The participants signed an informed consent form.

: Not applicable.

: The authors declare no competing interests.

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