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Authors
Pinto, Martina C. C. https://orcid.org/0000-0001-7412-3626
Dutra, Luciana
Lima, Rafael C.
Gusmão, Marcos Vinícius
Cipolatti, Eliane P.
Manoel, Evelin A.
Freire, Denise Maria G.
Pinto, José Carlos
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Funding
Funding for this research was provided by:
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Fundação de Amparo à Pesquisa do Estado da Bahia
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Article History
Accepted: 18 August 2025
First Online: 8 September 2025
Declarations
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: Not applicable.
: All authors provided their consent to participate.
: All authors provided their consent to publish their work.
: The authors declare no competing interests.The development of controlled-release formulations has boosted the pharmaceutical sector, highlighting the use of polymers as drug carriers. This study evaluated the chemical and enzymatic degradation of PMMA and PS matrices. A bibliometric analysis revealed a 100% increase in publications over 20 years. Despite PMMA’s recalcitrance, experimental essays revealed that enzymatic treatments showed potential for degradation. The study underscores the need for biodegradable alternatives in pharmaceuticals.
