Document is current
Any future updates will be listed below
-
Authors
Shih, Jheng-Hong
Chern, Edward https://orcid.org/0000-0002-9317-5410
-
Funding
Funding for this research was provided by:
National Science and Technology Council (112-2221-E-002 -101 -, 113-2320-B-002 -065 -)
- License Information
-
More Information
Article History
Accepted: 2 April 2025
First Online: 14 April 2025
Declarations
:
: All experimental animal procedures were approved by the Institutional Animal Care and Use Committee (IACUC) of National Taiwan University. (Approval No. NTU- 110-EL- 00162).
: Not applicable.
: Not applicable: the study did not involve human participants.
: This study established a robust protocol to differentiate human iPSCs into MSCs with superior characteristics and functionality, closely resembling adipose- and umbilical cord-derived MSCs. By leveraging decellularized porcine aorta as an ECM-rich scaffold, its excellent biocompatibility was demonstrated, supporting MSC attachment, growth, and chondrogenic differentiation. The findings highlighted the synergy between hiPSC-derived MSCs and ECM scaffolds, offering a promising avenue for therapeutic applications and advanced tissue engineering strategies.
: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
