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Authors
Yue, Wei
Yang, Yue
Miao, Yan
Li, Jinqi
Li, Shanshan
Yang, Yi
Zhang, Yingwen
Qian, Baohua
Li, Yanxin
Gu, Haihui
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (No. 32271007)
National Natural Science Foundation of China (No. 81970165)
Natural Science Foundation of Shanghai Municipality (23ZR1441000)
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Article History
Received: 23 October 2025
Accepted: 7 January 2026
First Online: 30 January 2026
Declarations
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: The ethics committee of the Children’s Medical Center affiliated with Shanghai Jiao Tong University approved the induction experiment for iPS cells (Approval title: Using iPSC Technology to Investigate Genetic Variant Profiles and Drug-Resistance Mechanisms Underlying Relapse in T-Cell Acute Lymphoblastic Leukemia Subclones; Approval No. SCMCIRB-K2014050; Date of Approval: October, 2014). Subsequent ethical clearance for human biological specimen utilization was obtained from the Naval Medical University Research Ethics Committee, conducted under the National Natural Science Foundation of China (Approval title: Effect and mechanism of PKA on generation of functional platelets from human iPS cells; Grant No. 81570185; Date of Approval: March, 2022). All peripheral blood samples were collected from donors following written informed consent in compliance with the Declaration of Helsinki principles.
: All authors agree to submission of the manuscript and agree to publication.
: The authors declare no competing interests.
