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Patterns and persistence of use, effectiveness, safety, clinical inertia, and adherence related to Levothyroxine treatment with real-world evidence. An observational, longitudinal and retrospective study

Crossref DOI link: https://doi.org/10.1007/s12020-025-04488-1

Published Online: 2026-02-16

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Valladales-Restrepo, Luis Fernando

Londoño-Cano, Diego Andrés

Muñoz-Velez, Carlos Mauricio

Soto-Romero, Lian Manuela

Tafur-Ramirez, Marlon Eleazart

Rojas-Varón, Maria José

Machado-Alba, Jorge Enrique
Funding

Funding for this research was provided by:

Technological University of Pereira
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Article History

Received: 22 September 2025

Accepted: 2 December 2025

First Online: 16 February 2026

Change Date: 19 February 2026

Change Type: Update

Change Details: The word 'Educativa' has been changed as "Universitaria" in affliation 2 and 3.

Declarations

:

: The authors declare no competing interests.

: The protocol was approved by the Bioethics Committee of the Universidad Tecnológica de Pereira (Technological University of Pereira) in the category of risk-free research (endorsement code: 27-130323). The ethical principles established by the Declaration of Helsinki were respected. According to the country’s regulations, observational studies conducted on databases and electronic patient records do not require informed consent.

: All authors agree to the publication of the submitted manuscript.

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