Pepe, Jessica https://orcid.org/0000-0002-3088-0673
Viviani, Arianna
Cipriani, Cristiana
Ciminelli, Bianca Maria
Jodice, Carla
Colangelo, Luciano
Forti, Marco
Santori, Rachele
Terreri, Sara
Minisola, Salvatore
Latini, Sara
Occhiuto, Marco
Malaspina, Patrizia
Novelletto, Andrea
Funding for this research was provided by:
Università degli Studi di Roma La Sapienza
Article History
Received: 24 January 2026
Accepted: 31 July 2026
First Online: 8 August 2026
Declarations
Ethics approval: The study was approved by the local Ethic Committee (“Comitato etico Lazio Area 1”; protocol number 7356). The Research was carried out complying with the World Medical Association Declaration of Helsinki. Written informed consent was obtained from the parents.
Conflict of interests: S.M. served as a speaker for Abiogen, Beijing Society Biomedical Engineering, Geopharma, Sandoz, UCB. He also served on the advisory board of Kyowa Kirin and Faes Farma. CC served as speaker, consultant and received travel reimbursement from Abiogen. She also served as consultant and on advisory board of IBSA and received travel reimbursement from Amgen. The other authors have no conflicts to declare.