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Molecular Profiling of Digestive Grade 3 Neuroendocrine Tumors Reveals a Shared Molecular Framework with Lower-Grade Tumors, Marked Heterogeneity, and Therapeutic Opportunities

Crossref DOI link: https://doi.org/10.1007/s12022-026-09918-y

Published Online: 2026-05-12

Published Print: 2026-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sciarra, Amedeo https://orcid.org/0000-0002-7550-0312
Libera, Laura https://orcid.org/0000-0003-2130-6669
Destro, Annarita https://orcid.org/0000-0001-5388-0353
Maragliano, Roberta https://orcid.org/0000-0002-6972-5080
Furlan, Daniela https://orcid.org/0000-0002-5958-5379
Guastafierro, Vincenzo https://orcid.org/0009-0000-4326-1970
Marchiori, Deborah https://orcid.org/0000-0001-8867-0938
Vanoli, Alessandro https://orcid.org/0000-0002-2976-7032
Gonzalez, Raul S. https://orcid.org/0000-0001-5526-4220
Letovanec, Igor https://orcid.org/0000-0002-0410-3491
Lazzi, Stefano https://orcid.org/0000-0002-2218-3771
La Rosa, Stefano https://orcid.org/0000-0003-1941-2403
Uccella, Silvia https://orcid.org/0000-0002-5714-7295
Funding

Funding for this research was provided by:

Università degli Studi dell'Insubria
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Text and Data Mining valid from 2026-05-12

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Article History

Received: 11 March 2026

Accepted: 28 April 2026

First Online: 12 May 2026

Declarations

:

: The Ethical Committee of the University Hospital of Varese has approved the present work (protocol n.0036374).

: Alessandro Vanoli, Stefano La Rosa and Silvia Uccella are members of the editorial board of Endocrine Pathology. Other authors have no competing interests to disclose.

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