Kempen, Bavo https://orcid.org/0000-0001-5326-4761
Depreitere, Bart https://orcid.org/0000-0002-7458-0648
Piper, Ian https://orcid.org/0000-0003-1434-6347
Poca, Maria https://orcid.org/0000-0002-3831-0536
Iencean, Stefan Mircea https://orcid.org/0000-0002-6230-8540
Garcia, Mireia https://orcid.org/0000-0003-0185-4705
Weitz, James https://orcid.org/0009-0006-9746-8022
Subramanian, Gayathri https://orcid.org/0000-0003-1771-4002
O’Kane, Roddy https://orcid.org/0009-0006-5933-6539
Zipfel, Julian https://orcid.org/0000-0003-4725-713X
Barzdina, Arta https://orcid.org/0000-0002-2877-891X
Pezzato, Stefano https://orcid.org/0000-0003-0921-0875
Jones, Patricia A. https://orcid.org/0009-0001-1192-1169
Lo, Tsz-Yan Milly https://orcid.org/0000-0003-0701-6534
,
Funding for this research was provided by:
Medical Research Council (MR/R004498/1)
Fonds Wetenschappelijk Onderzoek (1S12525N)
Laly Foundation, srl (Research Chair)
NHS Research Scotland
Article History
Received: 4 March 2025
Accepted: 2 May 2025
First Online: 3 June 2025
Declaration
:
: The authors declare that they have no competing interests.
: Ethical and other regulatory approvals were obtained in all 16 participating PICUs from seven countries (UK, Belgium, Spain, Romania, Latvia, Italy, and Germany). The study was registered with the National Health Service, National Health Service Research Scotland Permissions Coordinating Centre, and the Health Research Authority.