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Authors
Bögli, Stefan Yu https://orcid.org/0000-0001-5386-0811
Olakorede, Ihsane
Smith, Claudia Ann
Hutchinson, Peter
Czosnyka, Marek
Smielewski, Peter
Agrawal, Shruti
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Funding
Funding for this research was provided by:
Action Medical Research for Children’s Charity and Addenbrookes Charitable Trust (GN2609)
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (225270)
Patrick & Margaret Flanagan Skye Cambridge Trust Scholarship
NIHR
University of Zurich
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Article History
Received: 20 May 2025
Accepted: 7 August 2025
First Online: 8 September 2025
Conflict of interest
: ICM + is a software licensed by Cambridge Enterprise Ltd. MC and PS have a financial interest in a part of the licensing fee; the licensing fee was waived for this study.
: The STATRHIP study was approved by the Southwest-Central Bristol Research Ethics Committee as a research database study, in the first instance for five years (Ref: 18/SW/0053), which was subsequently renewed in March 2023 (Ref: 23/SW/0011) for five more years in view of COVID-19-related delays in study completion. The study was conducted in accordance with the ethical principles set forth in the 1964 Declaration of Helsinki and its subsequent revisions. Due to the observational nature of the acute phase of the project, a deferred consent for acute data collection and sharing was taken to allow for the acquisition of a bias-free sample. Informed consent was received from the patients’ legal guardians for data sharing and follow-up before discharge.
