Åkerlund, Cecilia A. I. https://orcid.org/0000-0003-4918-1482
Holst, Anders
Beqiri, Erta
Smielewski, Peter
Ercole, Ari
Nelson, David
,
Anke, Audny
Beer, Ronny
Bellander, Bo-Michael
Buki, Andras
Cabeleira, Manuel
Carbonara, Marco
Chieregato, Arturo
Citerio, Giuseppe
Clusmann, Hans
Czeiter, Endre
Czosnyka, Marek
Depreitere, Bart
Frisvold, Shirin
Helbok, Raimund
Kondziella, Daniel
Koskinen, Lars-Owe
Kowark, Ana
Menon, David K.
Meyfroidt, Geert
Moeller, Kirsten
Piippo-Karjalainen, Anna
Radoi, Andreea
Ragauskas, Arminas
Raj, Rahul
Rhodes, Jonathan
Rocka, Saulius
Rossaint, Rolf
Sahuquillo, Juan
Sakowitz, Oliver
Stocchetti, Nino
Sundström, Nina
Takala, Riikka
Tamosuitis, Tomas
Tenovuo, Olli
Unterberg, Andreas
Vajkoczy, Peter
Vargiolu, Alessia
Vilcinis, Rimantas
Wolf, Stefan
Younsi, Alexander
Zeiler, Frederick A.
Funding for this research was provided by:
Region Stockholm (Clinical postdoctoral appointment)
FP7 Health (602150)
ZNS - Hannelore Kohl Stiftung
One Mind
Integra LifeSciences
Karolinska Institute
Article History
Received: 28 December 2025
Accepted: 28 April 2026
First Online: 29 May 2026
Conflicts of interest
: The authors declare that they have no conflicts of interest.
: The CENTER-TBI study (EC grant 602150) has been conducted in accordance with all relevant laws of the European Union (EU) if directly applicable or of direct effect and all relevant laws of the country where the recruiting sites were located, including but not limited to, the relevant privacy and data protection laws and regulations (the “Privacy Law”), the relevant laws and regulations on the use of human materials, and all relevant guidance relating to clinical studies from time to time in force including, but not limited to, the ICH Harmonised Tripartite Guideline for Good Clinical Practice (CPMP/ICH/135/95) (“ICH GCP”) and the World Medical Association Declaration of Helsinki entitled “Ethical Principles for Medical Research Involving Human Subjects.” Informed consent was obtained from the patients and/or the legal representative/next of kin, accordingly to the local legislations, for all patients recruited in the core dataset of CENTER-TBI and documented in the e-CRF. Ethical approval was obtained for each recruiting site. The list of sites, ethical committees, approval numbers, and approval dates can be found on the following website: .