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Silencing KMT2A with siRNA induces apoptosis and cell cycle arrest in high-grade serous ovarian carcinoma cells by modulating GOF p53-dependent pathways, highlighting its potential as a therapeutic target

Crossref DOI link: https://doi.org/10.1007/s12032-025-03134-0

Published Online: 2025-12-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ghanbari, Mohammad

Haghi, Mehdi

Safaralizadeh, Reza

Baradaran, Behzad

Hosseinpour Feizi, Mohammad Ali
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Text and Data Mining valid from 2025-12-11

Version of Record valid from 2025-12-11
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Article History

Received: 16 June 2025

Accepted: 11 November 2025

First Online: 11 December 2025

Declarations

:

: The authors declare no competing interests.

: The study was conducted in accordance with the ethical principles of the Declaration of Helsinki (WMA) for human research and was approved by the Ethics Committee of University of Tabriz (IR.TABRIZU.REC.1404.016).

: Informed consent was obtained from all individual participants included in the study.

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