Document is current

Article History

Received: 12 August 2017

Accepted: 17 October 2017

First Online: 30 October 2017

Compliance with Ethical Standards

:

: The authors declare that they have no conflicts of interest.

: Experiments using human-derived cells were approved by the corresponding committees of the Spanish Advisory Committee for Human Tissue and Cell Donation and Use and of the University of Santiago de Compostela and authorized by the local government. The human postmortem samples used in the present study were obtained from the Neurological Brain Bank of Navarra (Hospital of Navarra, Pamplona, Spain). Brains were dissected at autopsy from donors who had given informed consent in accordance with the Brain Donation Program of the Government of Navarra (Government directive 23/2001). Monkey handling was conducted in accordance with the European Council Directive 86/609/EEC and with the Society for Neuroscience Policy on the Use of Animals in Neuroscience Research. The experimental design was approved by the Ethical Committee for Animal Testing of the University of Navarra (ref: 019/2008) as well as by the Department of Health of the Government of Navarra (ref: NA-UNAV-04-08). Rodent experiments were carried out in accordance with Directive 2010/63/EU and Directive 86/609/CEE and the Spanish RD/53/2013 and were approved by the corresponding committee at the University of Santiago de Compostela.