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Bispecific Antibody Fragment Targeting APP and Inducing α-Site Cleavage Restores Neuronal Health in an Alzheimer’s Mouse Model

Crossref DOI link: https://doi.org/10.1007/s12035-019-1597-z

Published Online: 2019-04-30

Published Print: 2019-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

He, Ping

Xin, Wei

Schulz, Philip

Sierks, Michael R. https://orcid.org/0000-0001-7301-230X
Funding

Funding for this research was provided by:

AZTE (Catalyst Fund)
License Information

Text and Data Mining valid from 2019-04-30
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Article History

Received: 6 August 2018

Accepted: 2 April 2019

First Online: 30 April 2019

Compliance with Ethical Standards

: All protocols for animal use were approved by the Institutional Animal Care and Use Committee (IACUC) of the Arizona State University at Tempe, Arizona. Experiments described here were carried out in accordance with good animal practice following NIH recommendations.

: M Sierks is a founder of Studio Biotherapeutics.