Davidson, Jennilee M. http://orcid.org/0000-0002-7996-1386
Wu, Sharlynn S. L.
Rayner, Stephanie L.
Cheng, Flora
Duncan, Kimberley
Russo, Carlo
Newbery, Michelle
Ding, Kunjie
Scherer, Natalie M.
Balez, Rachelle
García-Redondo, Alberto
Rábano, Alberto
Rosa-Fernandes, Livia
Ooi, Lezanne
Williams, Kelly L.
Morsch, Marco
Blair, Ian P.
Di Ieva, Antonio
Yang, Shu
Chung, Roger S.
Lee, Albert
Funding for this research was provided by:
Motor Neurone Disease Research Australia (IG1910, IG2029, IG2036, IG2221, Phyllis Diana Seman MND Research Grant, BLP1901, IG2308)
National Health and Medical Research Council (APP1095215, APP1107644, APP1176913, APP2020035)
Macquarie University
Article History
Received: 7 August 2022
Accepted: 15 April 2023
First Online: 27 May 2023
Declarations
:
: The control cases and the CCNF S621G patient tissues have been provided with written consent through regional brain donor programs from the NSW Brain Tissue Resource Centre, the Sydney Brain Bank, Australia, respectively. The CCNF S195R patient was recruited through brain donor program at the CIEN Tissue Bank in Spain. In compliance with the brain bank's protocols, an informed consent for brain donation was obtained for both Brain Banks. Patient fibroblasts were obtained from Macquarie University Neurodegenerative Diseases Biobank. The research conducted in this study was approved by Macquarie Human Research Ethics Committee, 5201600387. Patient fibroblasts were reprogrammed into induced pluripotent stem cells and characterized as pluripotent [CitationRef removed] with approval from the University of Wollongong Human Research Ethics Committee HE13/272.Post-mortem brain tissue for a patient was also obtained from a brain donor to the CIEN Tissue Bank. In compliance with the brain bank's protocols, an informed consent for brain donation was obtained intra vitam. The CIEN Tissue Bank is a brain bank registered and authorized as a biobank by the Spanish local Health and Biomedical Research authorities. Accordingly, the CIEN Tissue Bank complies with Spanish and European regulations concerning the use of human biological samples and personal data protection in biomedical research.
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: The authors declare that they have no competing interests.