Ahmed, Mhoriam
Spicer, Charlotte
Harley, Jasmine
Taylor, J. Paul
Hanna, Michael
Patani, Rickie
Greensmith, Linda http://orcid.org/0000-0002-7839-5052
Funding for this research was provided by:
Rosetrees Trust (M249-F2)
Brain Research Trust
Article History
Received: 8 May 2023
Accepted: 12 July 2023
First Online: 29 July 2023
Declarations
:
: All experimental work was carried out under licence from the UK Home Office (Scientific Procedures Act 1986) and was approved by the Animal Welfare and Ethical Review Board of UCL Institute of Neurology. Collection of fibroblast samples from patients and healthy individuals and their use in research have been ethically approved by the ‘Newcastle and North Tyneside 1 Research Ethics Committee’ with REC reference number 08/HO906/28 + 5 with signed written consent obtained from patients.
: Not applicable
: Post-mortem brain tissue was obtained from the Queen Square Brain Bank (QSBB) for Neurological disorders, UCL Institute of Neurology, Wakefield Street, London WC1N 1PJ under a Materials Transfer Agreement. The QSBB holds all individual consent for patient material.
: The authors declare no competing interests.