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An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain

Crossref DOI link: https://doi.org/10.1007/s12035-024-04209-1

Published Online: 2024-05-03

Published Print: 2024-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ji, Yelong

Ma, Yuanyuan

Ma, Yimei

Wang, Ying

Zhao, Xining

Xu, Li

Ge, Shengjin https://orcid.org/0000-0001-7778-7540
Funding

Funding for this research was provided by:

Shanghai Municipal Key Clinical Specialty (shslczdzk03603)

the research program of Zhongshan Hospital, Fudan University (2021ZSCX27)
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Article History

Received: 23 August 2023

Accepted: 27 April 2024

First Online: 3 May 2024

Declarations

:

: All animal procedures were conducted in accordance with the Guidelines for Care and Use of Laboratory Animals of Fudan University, and all efforts were made to minimize animal suffering. The study protocol was approved by the Ethics Committee of the Affiliated Zhongshan Hospital, Fudan University (approval: 202106021 S).

: Not applicable.

: The authors declare that there are no competing interests.

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