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Inhibition of Cathepsin B Ameliorates Murine Cognitive Dysfunction and Neuronal Damage in Ischemic Stroke by Inhibiting Mitochondrial Apoptosis and Drp1-Mediated Mitochondrial Fission

Crossref DOI link: https://doi.org/10.1007/s12035-025-05094-y

Published Online: 2025-05-30

Published Print: 2025-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jia, Hongyi

Zhang, Bingge

Han, Xiao

Yu, Pei

Xiong, Bocheng

Liu, Tiansu

Shan, Luchen

Yang, Xifei

Hou, Qinghua
Funding

Funding for this research was provided by:

The Key Basic Research Program of Shenzhen Science and Technology Innovation Commission (JCYJ20200109150717745)

NSFC (82471629,82171583)

Shenzhen Key Medical Discipline Construction Fund (SZXK069)

Sanming Project of Medicine in Shenzen Municipality (SZSM202211010)

Natural Science Foundation of Guangdong Province (2021A1515010111)

Shenzhen Science and Technology Innovation Commission Foundation and Applied Basic Fund (JCY20210324121804013)
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Text and Data Mining valid from 2025-05-30

Version of Record valid from 2025-05-30
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Article History

Received: 12 February 2025

Accepted: 19 May 2025

First Online: 30 May 2025

Declarations

:

: Ethics approval for animal work was provided by the Institutional Animal Care and Use Committee of Jinan University. (protocol number: 202310006).

: The authors declare no competing interests.

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