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Komagataella pastoris KM71H Attenuates Cognitive Deficits and Depressive-Like Behavior by the TLR4/NF-κB Signaling Pathway in an Aβ1-40-Induced AD-Like Mouse Model

Crossref DOI link: https://doi.org/10.1007/s12035-025-05267-9

Published Online: 2025-08-06

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Birmann, Paloma T.

Zugno, Giuliana Petiz

Sinott, Airton

Rodrigues, Rafael R.

Conceição, Fabricio R.

Sousa, Fernanda Severo Sabedra

Collares, Tiago

Seixas, Fabiana K.

Savegnago, Lucielli
Funding

Funding for this research was provided by:

CAPES

CNPQ

FAPERGS
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Text and Data Mining valid from 2025-08-06

Version of Record valid from 2025-08-06
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Article History

Received: 11 April 2025

Accepted: 25 July 2025

First Online: 6 August 2025

Declarations

:

: The experiments with animals were carried out in accordance with the Institutional Animal Care and Use Committee of the Federal University of Pelotas (approval number of the ethics committee: 026745/2021–90), affiliated with the National Council for Animal Experimentation Control (CONCEA).

: Not applicable.

: Not applicable.

: The authors declare no competing interests.

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