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Authors
Guo, Ying
Xie, Jianping
Luo, Haiyun
Yuan, Yun
Long, Fang
Meng, Jingyuan
Tan, Hui
Li, Yuanping
Cai, Bibo
Chen, Meiling
Yang, Liyan
Zhong, Jingmei
Zhu, Yanqing
Shao, Heng
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Funding
Funding for this research was provided by:
the National Natural Science Foundation of China (82060650)
the National Natural Science Foundation of China (82260242)
the Yunnan Province Young and Middle-aged Academic and Technical Leaders Reserve Talents Project (202405AC350045)
the Applied Basic Research Projects of Yunnan Province (202401AY070001-216)
Yunnan Province “Xingdian Talents Support Program” (XDYC-MY-2022-0012)
the Yunnan Provincial Clinical Research Center for Geriatric Diseases (2022YJZX-LN09)
the Yunnan Provincial Clinical Research Center for Geriatric Diseases (2023YJZX-LN20)
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Article History
Received: 24 June 2025
Accepted: 11 December 2025
First Online: 23 December 2025
Declarations
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: This study was approved by the Research Ethics Committee of the First People's Hospital of Yunnan Province (Approval No.: KHLL2023-KY116) and was conducted in accordance with the Declaration of Helsinki. The privacy rights of human subjects have been observed and that informed consent was obtained for experimentation with human subjects. The study was registered with the National Health Insurance Information Platform and the Medical Research Registration Information System ( ), registration number MR-53–24-005139. All animal experimental procedures were performed according to the protocols approved by Kunming Medical University Animal Ethics Review Committee (No. kmmu20240223).
: All participants provided written informed consent for publication of anonymized data.
: The authors declare no competing interests.
