Svirsky, Sarah E.
Roberts, Andrea
Parry, Madison
Henchir, Jeremy
Dixon, C. Edward
Jackson, Travis C.
Chang, Yuefang
Conley, Yvette
Puccio, Ava M.
Carlson, Shaun W. https://orcid.org/0000-0002-1413-5075
Article History
Received: 13 May 2025
Accepted: 20 January 2026
First Online: 12 February 2026
Declarations
:
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the University of Pittsburgh and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the Institutional Review Board of the University of Pittsburgh (STUDY19030228). This study is approved for future studies to be completed on previously collected biospecimen samples, genetic and outcome data. All data are coded with a unique identifying number, different from the patient’s medical record number or social security number, to maintain confidentiality.
: Due to the nature of severe TBI, written informed consent was signed by the legal authorized representative prior to participation in any study procedures. The study is also approved for a waiver of consent for the collection of biospecimens up to 48 h after admission when the LAR is not present at the research site.
: The authors declare no competing interests.