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Inflachromene Blocks Neuronal HMGB1 Translocation to Mitigate Hippocampal TLR4–NF-κB–Mediated Neuroinflammation and Depression-Like Behavior After Spinal Cord Injury

Crossref DOI link: https://doi.org/10.1007/s12035-026-05846-4

Published Online: 2026-04-14

Published Print: 2026-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhou, Wu

Hei, Bo

Liu, Zhixin

Wang, Zhihua

Li, Chengcai

Ding, Zihan

Li, Meihua
Funding

Funding for this research was provided by:

Natural Science Foundation of Jiangxi Province (20242BAB26132)

Double Thousand Plan of Jiangxi Province (Jxsq2023101024)

National Natural Science Foundation of China (82260248)
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Text and Data Mining valid from 2026-01-01

Version of Record valid from 2026-01-01
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Article History

Received: 5 November 2025

Accepted: 1 April 2026

First Online: 14 April 2026

Declarations

:

: Not applicable.

: The animal experiments were performed in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals and approved by the Ethics Committee of the First Affiliated Hospital of Nanchang University (Approve Number: CDYFY-IACUC-202302QR050).

: Not applicable.

: The authors declare no competing interests.

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