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Authors
Li, Yuhan
Luan, Yansong
Li, Jianning
Song, Hui
Li, Yan
Qi, Hi
Sun, Bo
Zhang, Peng
Wu, Xianxian
Liu, Xing
Yang, Yanhui
Tao, Wufan
Cai, Lei
Yang, Zhiwei
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (81670798 and 81460166, 81800402)
Chinese Ministry of Education (Z2016039)
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Article History
Received: 23 April 2020
Accepted: 12 September 2020
First Online: 10 October 2020
Compliance with ethical standards
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: Yuhan Li, Yansong Luan, Jianning Li, Hui Song, Yan Li, Hi Qi, Bo Sun, Peng Zhang, Xianxian Wu, Xing Liu, Yanhui Yang, Wufan Tao, Lei Cai, Zhiwei Yang, Yi Yang declare that they have no conflict of interest.
: The collection of these human liver specimens was performed in accordance with the Ethical Committee on Human Research of the participating hospitals. All the patients were informed of the usage of the samples and written consent forms were obtained prior to the initiation of the study. Then mice were injected through the tail vein with 30 μg exosomes containing either a negative control (miR-NT) or miRNA mimics (miR-199a) and NC inhibitor or miRNA inhibitor (antimiR-199a) bi-weekly for 3 weeks. All animal procedures were conducted according to the protocols approved by the Committee of Animal Use for Research and Teaching of Ningxia Medical University, Yinchuan, China (SCXK (Ning) 2015-0001).
